Relaxant effects of L -citrulline in rabbit vascular smooth muscle
نویسندگان
چکیده
منابع مشابه
L-Citrulline, the by-product of nitric oxide synthesis, decreases vascular smooth muscle cell proliferation.
Endothelium injury plays an important role in atherosclerosis. Damage to the endothelium results in vascular smooth muscle cell proliferation. Natriuretic peptides present a potent antimitogenic action, mediating their biological effects via the binding of guanylate cyclase-linked atrial natriuretic peptide (ANP) receptor and the production of cyclic GMP. In a previous study, we demonstrated th...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1998
ISSN: 0007-1188
DOI: 10.1038/sj.bjp.0702051